Researched and written by Mike Shertz, MD/18D, not AI
🕖 Reading Time, 2 minutes
One such product, OctaplasLG is a freeze dried plasma approved by the FDA under an emergency use authorization for the military in 2024.
Functionally it is similar to French freeze dried plasma, which has been used by SOCOM previously. It is shelf stable between 2 to 25°C up to 24 months.
The plasma itself is from blood groups A and AB collected from pulled donor plasma comprising anywhere from 370 to 1520 individual donations.
The package contains dried plasma in a glass bottle, 190 mL of sterile water for injection, a transfer set and separate transfusion set. The transfer set is used to spike both the IV bag as well as the glass container. There is a vent next to the spike which needs to be opened for the water to flow into the glass bottle.
The glass bottle containing freeze dried plasma is then swirled to dissolve the powder. Don’t shake it or it will foam. Within 15 minutes it should be fully in solution and ready to use.
To administer the reconstituted, freeze dried plasma, the included infusion set is used similar to traditional blood or IV infusion sets.
Once reconstituted, it is shelf stable for eight hours at room temperature (25°C.)
Source:
EUA Fact Sheet for Health Care Professionals or Other Authorized Providers octaplasLG Powder
The Use of Dried Plasma in the Deployed Trauma System and Contingency Operations , CPG ID:103
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